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Danaher Inc
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Journal: Frontiers in Oncology
Article Title: Primary extraovarian adult granulosa cell tumor of the greater omentum: a case report and literature review
doi: 10.3389/fonc.2025.1689815
Figure Lengend Snippet: Pathological characteristics of the extraovarian adult granulosa cell tumor of the greater omentum. (A–D) Photomicrograph of the tumor (H&E stain). (A) The tumor is encapsulated (H&E stain, 40×magnification, Scale bar: 625 μm). (B) Neoplastic cells are arranged in cord-like and ribbon-like patterns (H&E stain, 100×magnification, Scale bar: 200 μm). (C) Call-Exner bodies are visible (H&E stain, 200×magnification, Scale bar: 100 μm). (D) The tumor is composed of round, oval, or polygonal cells with ill-defined cytoplasmic borders imparting a syncytial appearance. The scant cytoplasm ranges from pale to eosinophilic. Nuclei are round, oval, or angular with finely dispersed chromatin and inconspicuous nucleoli. Longitudinal nuclear grooves and coffee-bean shaped nuclei are present(H&E stain, 400×magnification, Scale bar: 50 μm). (E–I) Photomicrograph of immunohistochemical staining. Immunohistochemistry staining is positive for α-inhibin (E) , SF-1 (F) , FOXL2 (G) , WT-1 (H) . (I) Ki-67 Proliferation Index was 20% (IHC stain, 200× magnification, Scale bar: 100 μm).
Article Snippet:
Techniques: Staining, Immunohistochemical staining, Immunohistochemistry
Journal: iScience
Article Title: CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
doi: 10.1016/j.isci.2024.109978
Figure Lengend Snippet:
Article Snippet:
Techniques: Recombinant, Protease Inhibitor, Membrane, Saline, Electron Microscopy, RNA Sequencing Assay, Software, Cytometry, Microscopy, Polymer